Eyelid movements during blinking in patients with Parkinson's disease
Identifieur interne : 003436 ( Main/Exploration ); précédent : 003435; suivant : 003437Eyelid movements during blinking in patients with Parkinson's disease
Auteurs : Marko Korošec [Slovénie] ; Ignac Zidar [Slovénie] ; Dik Reits [Pays-Bas] ; Craig Evinger [États-Unis] ; Frans Vanderwerf [Pays-Bas]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-08.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Adult, Age of Onset, Aged, Antiparkinson Agents (therapeutic use), Blinking, Blinking (physiology), Eyelid, Eyelids (physiology), Female, Human, Humans, Kinematics, Male, Middle Aged, Movement, Nervous system diseases, Parkinson Disease (drug therapy), Parkinson Disease (physiopathology), Parkinson disease, Parkinson's disease, blink kinematics, blink rate, eyelid movements.
- MESH :
- chemical , therapeutic use : Antiparkinson Agents.
- drug therapy : Parkinson Disease.
- physiology : Blinking, Eyelids.
- physiopathology : Parkinson Disease.
- Adult, Age of Onset, Aged, Female, Humans, Male, Middle Aged, Movement.
Abstract
We examined eyelid movements during spontaneous, voluntary, and trigeminal reflex blinks in 16 patients with mild to moderate Parkinson's disease (PD) off medication and 14 controls. Voluntary and reflex blink amplitudes tended to be smaller than normal for PD patients, whereas eyelid kinematics (amplitude–maximum velocity relationship) for all three blink types were normal. Spontaneous blink rate was less than normal for 10 patients and abnormally high for 6 patients. A significant positive correlation between spontaneous blink amplitude and blink rate was found. These observations suggest that PD modifies the gain of a premotor blink circuit shared by spontaneous, voluntary, and reflex blinks. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.20930
Affiliations:
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Le document en format XML
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2006-08">2006-08</date><biblScope unit="vol">21</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="page" from="1248">1248</biblScope><biblScope unit="page" to="1251">1251</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">698FB06DAA7DED13EFD0649DEEF2A2313746A857</idno><idno type="DOI">10.1002/mds.20930</idno><idno type="ArticleID">MDS20930</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Age of Onset</term><term>Aged</term><term>Antiparkinson Agents (therapeutic use)</term><term>Blinking</term><term>Blinking (physiology)</term><term>Eyelid</term><term>Eyelids (physiology)</term><term>Female</term><term>Human</term><term>Humans</term><term>Kinematics</term><term>Male</term><term>Middle Aged</term><term>Movement</term><term>Nervous system diseases</term><term>Parkinson Disease (drug therapy)</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson disease</term><term>Parkinson's disease</term><term>blink kinematics</term><term>blink rate</term><term>eyelid movements</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiparkinson Agents</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Blinking</term><term>Eyelids</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Age of Onset</term><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Movement</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Cinématique</term><term>Clignement palpébral</term><term>Homme</term><term>Parkinson maladie</term><term>Paupière</term><term>Système nerveux pathologie</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We examined eyelid movements during spontaneous, voluntary, and trigeminal reflex blinks in 16 patients with mild to moderate Parkinson's disease (PD) off medication and 14 controls. Voluntary and reflex blink amplitudes tended to be smaller than normal for PD patients, whereas eyelid kinematics (amplitude–maximum velocity relationship) for all three blink types were normal. Spontaneous blink rate was less than normal for 10 patients and abnormally high for 6 patients. A significant positive correlation between spontaneous blink amplitude and blink rate was found. These observations suggest that PD modifies the gain of a premotor blink circuit shared by spontaneous, voluntary, and reflex blinks. © 2006 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Pays-Bas</li><li>Slovénie</li><li>États-Unis</li></country><region><li>Hollande-Méridionale</li><li>État de New York</li></region><settlement><li>Rotterdam</li></settlement></list><tree><country name="Slovénie"><noRegion><name sortKey="Korosec, Marko" sort="Korosec, Marko" uniqKey="Korosec M" first="Marko" last="Korošec">Marko Korošec</name></noRegion><name sortKey="Zidar, Ignac" sort="Zidar, Ignac" uniqKey="Zidar I" first="Ignac" last="Zidar">Ignac Zidar</name></country><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Reits, Dik" sort="Reits, Dik" uniqKey="Reits D" first="Dik" last="Reits">Dik Reits</name></region><name sortKey="Vanderwerf, Frans" sort="Vanderwerf, Frans" uniqKey="Vanderwerf F" first="Frans" last="Vanderwerf">Frans Vanderwerf</name></country><country name="États-Unis"><region name="État de New York"><name sortKey="Evinger, Craig" sort="Evinger, Craig" uniqKey="Evinger C" first="Craig" last="Evinger">Craig Evinger</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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